
DERMA-CODE™ NAD+ • PDRN • 6 Peptides Facial Moisturizer - 1.7 oz / 48g
OVERVIEW
This 1.7 oz (48g) clinical moisturizer combines NAD+ (NAD plus) with PDRN & 6 peptides
A clinical-performance moisturizer engineered for biological balance and restoration. Formulated with NAD+ (NAD plus), PDRN, and a six-peptide complex, it supports cellular energy, barrier strength, and visible renewal. The texture absorbs cleanly, delivering hydration without film or heaviness.
Designed to work synergistically with the DERMA-CODE™ Facial Serum or as a standalone treatment, it helps maintain resilience, smoothness, and long-term barrier integrity. Each concentration serves a biological purpose—no filler ingredients, no cosmetic illusion. Experience the power of NAD plus skincare with evidence-based hydration.
DERMA-CODE™ formulas are developed under oxygen-controlled conditions to preserve the activity of sensitive actives like NAD+ and PDRN, helping maintain molecular stability from production to final use. Each product is sealed in protective, light-shielding packaging designed to minimize oxidation and contamination while maintaining ingredient potency. Our ingredient callouts exist for transparency, not hype, featuring true NAD+, salmon-derived PDRN (Sodium DNA), and a six-peptide complex selected for synergistic support of skin texture, hydration, and visible balance. Every formula undergoes internal stability and compatibility testing to confirm active preservation and long-term integrity. At DERMA-CODE™, trust is earned through evidence, clarity, and uncompromising formulation science.
THE SCIENCE
DERMA-CODE™ NAD+ (NAD Plus) • PDRN • 6 Peptides Facial Moisturizer
With PDRN, NAD+ (NAD plus), and 6 Peptides in meaningful concentrations
The Philosophy
DERMA-CODE™ represents a scientific approach to skincare built on precision, transparency, and trust.
Every ingredient serves a biological purpose, and every concentration is meaningful.
No parfum, no dyes, no fillers.
This is a barrier-supportive facial moisturizer engineered for dry, normal, and combination skin. It works in harmony with the skin's lipid balance to deliver hydration, repair, and visible restoration.
NAD+ (NAD Plus): Cellular Energy and Barrier Recovery
Nicotinamide Adenine Dinucleotide (NAD+, also known as NAD plus) is a vital coenzyme present in every living cell. It supports the skin's energy metabolism and natural repair processes that decline with age and stress.
Functions supported by ingredient research:
• Helps fuel cellular ATP energy production for renewal and vitality
• Supports DNA-maintenance pathways involved in repair and longevity
• Enhances lipid synthesis for a stronger, more resilient barrier
• Helps defend against oxidative and environmental stress
DERMA-CODE™ delivers stabilized active NAD+ (NAD plus) in meaningful amounts, ensuring direct bio-availability for visible improvement in tone, resilience, and hydration.
PDRN: Regeneration and Elasticity Support
Polydeoxyribonucleotide (PDRN) is a purified DNA polymer derived from salmon DNA. It provides essential nucleic-acid fragments that signal renewal and tissue recovery.
Refined to a low-molecular-weight range of approximately 50 to 300 kDa, this PDRN achieves superior compatibility and effective epidermal absorption rather than remaining on the surface. This enables efficient cellular signaling for visible regeneration, elasticity, and hydration.
Supported skin benefits include:
• Encourages fibroblast activity and collagen support
• Promotes skin-density recovery for smoother, firmer texture
• Helps soothe visible irritation and reduce signs of sensitivity
• Improves the look of moisture retention and radiance
PDRN is used at meaningful concentration levels to support a visibly smoother, more supple complexion that reflects true skin restoration.
Six-Peptide Complex: Structure, Firmness, and Renewal
A synergistic combination of six short-chain peptides provides advanced communication between skin layers, helping maintain elasticity and balance.
1. Acetyl Hexapeptide-8 – often nicknamed "Botox-like peptide" for its smoothing action on expression lines.
2. Palmitoyl Tripeptide-1 – collagen-mimetic peptide that supports firmness and elasticity.
3. Palmitoyl Tripeptide-8 – helps calm and stabilize reactive skin while supporting barrier recovery.
4. Acetyl Heptapeptide-4 – enhances visible smoothness and contributes to a revitalized appearance.
5. Oligopeptide-1 (EGF-like peptide) – supports natural skin renewal and improved tone.
6. Heptapeptide-6 – reinforces structural integrity and overall skin density.
Together, these peptides create a multi-dimensional network that supports repair, balance, and visibly renewed texture.
Barrier and Hydration Support Matrix
• Ceramide Complex (NP, EOP, Phytosphingosine, Cholesterol): reinforces lipid structure and strengthens the barrier against moisture loss.
• Niacinamide: supports even tone, barrier function, and surface refinement.
• Squalane and Shea Butter: deliver balanced emollience and lasting hydration.
• Panthenol and Beta-Glucan: soothe sensitivity and promote surface resilience.
• Trehalose and Sodium Hyaluronate: maintain water balance and skin softness.
• Green Tea and Licorice Root Extracts: provide antioxidant protection and a more even appearance.
• Tocopherol (Vitamin E): shields against oxidative stress and supports lipid stability.
Each component works synergistically to restore hydration equilibrium and comfort across dry, normal, and combination skin types.
Visible Performance
• Skin feels deeply hydrated and balanced
• Texture appears smoother and more refined
• Barrier strength and elasticity visibly improve
• Complexion looks calm, bright, and restored
Consistent use supports sustained barrier stability and a visibly healthy glow.
How It Pairs with the DERMA-CODE™ Serum
This moisturizer was developed to work in synergy with the DERMA-CODE™ NAD+ (NAD plus) • PDRN • 6 Peptides Facial Serum, extending its reparative and hydrating effects. When layered after the serum, it reinforces barrier integrity, locks in moisture, and amplifies the visible results of both PDRN and peptide activity.
It also performs beautifully as a standalone treatment, delivering balanced hydration, barrier restoration, and visible renewal for those seeking a complete, single-step solution.
Each use supports smoother texture, improved elasticity, and a calm, refined complexion.
Results Over Time
DERMA-CODE™ formulas are designed to work with the skin's natural renewal cycle. Progressive improvement becomes visible with continued use, reflecting authentic biological performance rather than surface illusion.
With continued use you can expect:
• Improved elasticity from peptide and PDRN synergy
• Stronger barrier reinforced by ceramides, cholesterol, and niacinamide
• Refined, smoother texture through consistent hydration and balanced renewal
• More even tone and radiance from antioxidant and brightening actives
• Comfort and resilience as the formula helps restore barrier balance
Consistent application delivers a visibly stronger, smoother, more radiant complexion that continues to improve with time.
HOW TO USE
Apply a small amount to clean, damp, or dry skin as needed for hydration and barrier support. Suitable for both face and neck.
For optimal results, apply after the DERMA-CODE™ NAD+ • PDRN • 6 Peptides Facial Serum to reinforce visible barrier recovery and lock in actives.
Use morning and evening or as needed for hydration maintenance.
TRANSPARENCY & INGREDIENTS
Full Ingredient List (INCI)
Water (Aqua), Glycerin, Squalane, Propanediol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Niacinamide, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Dimethicone, Sodium DNA, Panthenol, Polysorbate 60, Phenoxyethanol, Nicotinamide Adenine Dinucleotide, Ceramide NP, Trehalose, Beta-Glucan, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Tocopherol, Ethylhexylglycerin, Sodium Hyaluronate, Cholesterol, Ceramide EOP, Carbomer, Hydroxyethylcellulose, Caprylhydroxamic Acid, Phytosphingosine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-8, Acetyl Heptapeptide-4, Oligopeptide-1, Heptapeptide-6, Acetyl Hexapeptide-8, Triethanolamine.
Facial Moisturizer
Engineered for biological performance, not cosmetic illusion.
DERMA-CODE™ is not a cover-up brand. We formulate for genuine skin regeneration, not short-term effects. Every concentration is purposeful, every molecule delivers function, and consistent use reflects real cellular progress, not marketing tricks.
A formula built on Precision, Transparency, and Trust.
Transparency Note
DERMA-CODE™ formulas are cosmetic skincare. Ingredient science is presented for educational transparency and should not be interpreted as medical advice or treatment claims.
Caution
For external use only. Avoid direct contact with eyes. Discontinue use if irritation occurs. Keep out of reach of children.
Allergen Warning
Contains ingredients sourced from salmon and soy. Avoid use if allergic.
FAQS
WHAT MAKES THIS MOISTURIZER DIFFERENT?
Our Universal Barrier Repair Moisturizer combines NAD+ precursors, low molecular weight PDRN, and 6 targeted peptides in a clinical-grade formula designed for maximum cellular renewal and barrier protection.
HOW DO I USE THE MOISTURIZER?
Apply a small amount to clean skin once or twice daily. Can be used as a standalone moisturizer or layered after serum for enhanced results. Perfect for morning and evening use.
WHAT SKIN TYPES IS THIS FOR?
Suitable for all skin types. The lightweight yet nourishing formula provides barrier repair without heaviness, making it ideal for sensitive, dry, combination, and mature skin.
WHEN WILL I SEE RESULTS?
Most users notice improved hydration and skin texture within 1-2 weeks, with significant improvements in barrier function, firmness, and overall skin quality by 6-8 weeks.
CAN I USE THIS ALONE OR DO I NEED THE SERUM?
The moisturizer works beautifully on its own for barrier repair and hydration. For maximum cellular renewal and anti-aging results, pair it with our NAD+ PDRN Serum in the Synergy Duo.
WHERE CAN I LEARN MORE ABOUT THE SCIENCE?
Explore our in-depth research on NAD+ cellular energy, low molecular weight PDRN, and our 6-peptide matrix on the DERMA-CODE™ Science blog.