DERMA-CODE™ embodies a scientific skincare model built on three pillars: Precision, Transparency, and Trust.
Every molecule is functional, every concentration meaningful, and every mechanism of action rooted in molecular science.
No parfum, no dyes, and no filler compounds are used. This formula is a clinical-grade bio-repair system designed for sensitive, compromised, or aging skin.

NAD+ (NAD Plus): Cellular Energy and DNA Integrity

Nicotinamide Adenine Dinucleotide (NAD+, also known as NAD plus) is the essential coenzyme in cellular respiration and repair. As NAD+ levels decline with age, the skin's ability to maintain energy, manage oxidative stress, and repair visible damage also declines.

Functions supported by ingredient research:
• Fuels cellular ATP energy production for renewal and vitality
• Supports DNA-maintenance and SIRT1 pathways involved in repair and longevity
• Promotes balanced lipid-barrier activity through NADPH/NADH cycling
• Helps defend against environmental oxidative stress

DERMA-CODE™ delivers stabilized active NAD+ (NAD plus) in meaningful amounts, ensuring bioavailability for visible rejuvenation and vitality.

PDRN: Molecular Support for Renewal

Polydeoxyribonucleotide (PDRN) is a DNA polymer fraction derived from salmon DNA fragments that serve as natural nucleic-acid substrates and A₂A receptor modulators.

Our PDRN is refined to a low-molecular-weight range of approximately 50 to 300 kilodaltons (kDa). This optimized size allows enhanced epidermal penetration and efficient signaling for visible regeneration and elasticity.

Supported skin benefits include:
• Encourages fibroblast activity and collagen-matrix support
• Promotes micro-circulation for improved tone and radiance
• Helps calm visible irritation and maintain a balanced complexion
• Improves the look of elasticity, hydration, and smoothness

At 2%, PDRN delivers measurable improvement in hydration, density, and refined skin texture, supporting healthier, more resilient skin.

Six-Peptide Complex: Bio-Signal Architecture

A synergistic network of six biomimetic peptides designed to support visible firmness and smoothness through advanced cellular communication:

1. Acetyl Hexapeptide-8 – often called "Botox-like peptide" for its visible smoothing effect on expression lines.
2. Palmitoyl Tripeptide-1 – collagen-fragment mimic that signals skin to maintain elasticity.
3. Palmitoyl Tetrapeptide-7 – helps reduce visible inflammation-related dullness for even tone.
4. Copper Tripeptide-1 – supports surface repair, clarity, and balanced texture.
5. Palmitoyl Pentapeptide-4 (Matrixyl): reinforces dermal thickness and smoothness.
6. Acetyl Octapeptide-3: enhances surface relaxation effects for deeper wrinkles.

Together, they form a multi-pathway communication system that supports visible firmness, smoothness, and balance.

Bio-Compatible Support Matrix

• Niacinamide: supports barrier integrity and refines texture.
• Squalane: skin-identical emollient delivering lightweight moisture.
• Panthenol and Allantoin: calm sensitivity and promote surface comfort.
• Sodium Hyaluronate: binds hydration within the skin's matrix.
• Tocopherol (Vitamin E): helps defend against oxidative stress.
• Lecithin: stabilizes and enhances ingredient absorption.
• Hydroxyethylcellulose and Carbomer: maintain lightweight gel structure without film buildup.

Each ingredient contributes to optimal absorption, comfort, and skin balance.